IDP work group charter

Intrinsically Disordered Proteins Working Group Charter

 

Submitted: 2019-08-20

Template Rev2016b

1. Administrative Section

 

Status (New/Update): New

 

Group Name:

HUPO PSI Intrinsically Disordered Proteins Working Group (PSI-IDP WG)

 

Chair (with affiliation and current email address):

Norman Davey - The Institute of Cancer Research, London, UK (norman.davey@icr.ac.uk)

 

Co-Chairs (1 or 2) (with affiliation and current email address):

Silvio C. E. Tosatto - University of Padua, Padua, Italy (silvio.tosatto@unipd.it)

Zsuzsanna Dosztányi - Eötvös Loránd University, Budapest, Hungary (dosztanyi@caesar.elte.hu)

 

Secretary:

Bálint Mészáros - Eötvös Loránd University, Budapest, Hungary (bmeszaros@caesar.elte.hu)

 

Other officers (optional) (with affiliation and current email address):

Editor(s): Nicolás Palopoli - Universidad Nacional de Quilmes, Buenos Aires, Argentina (npalopoli@unq.edu.ar), Rita Pancsa - Research Centre for Natural Sciences, HAS, Budapest, Hungary (pancsa.rita@ttk.mta.hu), Kim Van Roey - European Molecular Biology Laboratory, Heidelberg, Germany (kimvanroey@hotmail.com)

Minimal Reporting Requirements Coordinator(s): Norman Davey - The Institute of Cancer Research, London, UK (norman.davey@icr.ac.uk)

Ontology Coordinator(s): Toby Gibson - European Molecular Biology Laboratory, Heidelberg, Germany (toby.gibson@embl.de); Peter Tompa - Vrije Universiteit Brussel, Brussels, Belgium (peter.tompa@vub.be)

Website Maintainer(s): Damiano Piovesan - University of Padua, Padua, Italy (damiano.piovesan@unipd.it)

 

Mailing list

psi-idp-dev@ebi.ac.uk

2. Description and objectives

Focus and Purpose

The PSI-IDP working group is composed of academic, government, and industry researchers, software developers, and database curators and managers. The main goals of the PSI-IDP working group are to:

  1. define the community PSI-IDP XML, JSON and TAB exchange formats to permit the dissemination and storage of data relating to Intrinsically Disordered Proteins/Regions (IDP/IDR) structure and function.
  2. define the Minimum Information About Disordered Experiments (MIADE) guidelines to standardise the description of IDP experiments.
  3. create the ontologies and controlled vocabularies required to define the functional and structural aspects of IDRs, and the technical aspects of the exchange formats and minimum information guidelines.
  4. define the best practice guidelines for the curation of IDP literature and the annotation of IDP data.
  5. support the implementation of the PSI-IDP exchange formats, controlled vocabularies and best practice guidelines by the tools and resources developed by the IDP community.

 

Current projects of the PSI-IDP working group are:

  1. definition and development of the MIADE guidelines.
  2. definition and development of the PSI-IDP exchange formats, working together with the PSI-MI workgroup.
  3. development of the PSI-IDP controlled vocabulary to describe the technical aspects of IDP experiments and the sequence-level structural inferences derived from them.

Goals/Milestones

 

Goal 1: Completion of the MIADE standard defining the minimal fundamental parameters to describe a disorder experiment, based on simple use cases

Goal 2: Completion of the 1.0 version of the PSI-IDP TAB exchange format to represent, in a simple but unambiguous manner, an entry adhering to the MIADE guidelines for the description of the structural state of a protein region

Goal 3: Completion of the 1.0 version of the PSI-IDP XML and JSON exchange formats to enable the unequivocal representation of the experimental setup and results of analyses investigating the structural state of a protein region

Goal 4: Work together with the PSI-MI Working Group to set up a protocol for integrating data describing interactions mediated by IDRs into core data resources for molecular interactions

Goal 5: Defining the scope and priorities for version 1.0 of the controlled vocabulary for IDP exchange formats and develop the controlled vocabulary required for 1.0 version of the PSI-IDP exchange formats.

 

Milestone 1: Submission of a manuscript to announce the PSI-IDP Working Group

Milestone 2: Setting up the PSI-IDP Working Group website/GitHub page to serve as a platform for the dissemination of developed exchange formats, standards, guidelines and controlled vocabularies

 

Website

http://www.psidev.info/groups/intrinsically-disordered-proteins

 

Tags

Intrinsic Disorder, Intrinsically Disordered Proteins, Intrinsically Disordered Regions, Protein Structure, Protein Interactions, Protein Function

Tags
Charter
IDP