Mission Statement
The HUPO Proteomics Standards Initiative (PSI) defines community standards for data representation in proteomics to facilitate data comparison, exchange and verification. The PSI was founded at the HUPO meeting in Washington, April 28-29, 2002 (see Science 296, 827).
News
- The 7th Annual World Congress HUPO 2008 will be held from 16 – 20 August 2008 in Amsterdam, the Netherlands. Current PSI activities will be discussed on Sunday, August 17, 09:30-12:00.
- The last PSI spring meeting took place on April 23-25, 2008 in Toledo, Spain.
- The PSI spring meeting 2007 took place April 23-25, 2007 in Lyon, France, with ca. 90 participants.
- The public review by Nature Biotechnology has now been completed for the PSI-related manuscripts.
Work groups
The main organisational unit of the Proteomics Standards Initiative is the work group. Currently, there are the following work groups:
- Gel Electrophoresis (GEL)
- Mass Spectrometry (MS)
- Molecular Interactions (MI)
- Protein Modifications (MOD)
- Proteomics Informatics (PI)
- Sample Processing (SP)
Inter-group activities
To ensure consistency between work group deleverables, the PSI also maintains the following inter-group activities:
Organisation
To know the roles and responsibilities inside the different PSI workgroups, please visit this link.
Project status
The following table summarises the status of the PSI activities:
| Working Group | Reporting Guidelines (MIAPE) | Data exchange format | Controlled vocabulary | ||||||
| Cross-WG projects | MIAPE Principles Document |
4
|
FuGE (milestone 3) |
4
|
FuGO |
1
|
|||
| Study design and sample generation |
1
|
||||||||
| Statistical analysis of data |
0
|
||||||||
| Gel | Gel electrophoresis |
4
|
GelML (milestone 1) |
3
|
Gel CV |
2
|
|||
| Gel image informatics |
2
|
GelInfoML |
2
|
||||||
| Sample Processing | Chromatography |
3
|
spML (milestone 1) |
3
|
SP CV |
1
|
|||
| Capillary electrophoresis |
3
|
||||||||
| Sample Processing |
0
|
||||||||
| Mass Spectrometry | Mass spectrometry |
4
|
mzData (v1.05) |
4
|
MS CV |
3
|
|||
| Mass spectrometry informatics |
4
|
analysisXML |
2
|
||||||
| Molecular Interactions | Molecular interactions |
5
|
MIF |
5
|
PSI-MI (v2.5) |
5
|
| Color key: |
(0) Nothing
|
(1) Drafting
|
(2) Alpha
|
(3) Beta
|
(4) Release
|
(5) Published
|
Acknowledgements
PSI activities have been/are supported by:
- The Human Proteome Organisation (HUPO).
- The HUPO Plasma Proteome Project.
- EU ProDaC grant (LSHG-CT-2006-036814).
- Sporsors of the PSI Meetings/Workshops: Agilent Technologies, American Chemical Society, Applied Biosystems, BBSRC, Bruker Daltonics, DKFZ, EBI Industry Program, Eli Lilly, GE Healthcare, Genebio, Genologics, I-HUPO, IPSoc, Novartis, Roche, Serono, Syngenta, Swiss Institute of Bioinformatics, Swiss Proteomics Society, Thermo Electron.
